ISSN 1129-7298
J Vasc Access 2017; 00 (00) :000-000
DOI: 10.530/jva.5000762

Health-related quality of life of cancer patients with peripherally inserted central catheter: a pilot study.

Kang J1Chen W1Sun W1Ge R1Li H1Ma E1Su Q2Cheng F3Hong J4Zhang Y5Lei C6Wang X7Jin A8Liu W9.



This pilot exploratory study aimed to compare the health-related quality of life (HRQOL) among patients diagnosed with different types of cancer receiving peripherally inserted central catheters (PICCs).  


A multicenter cross-section study of cancer patients with PICCs was performed from February 1, 2013 to April 24, 2014. The primary objective of this study was to compare HRQOL in different cancer type patients with PICC. HRQOL was examined based on European Organisation for Research and Treatment of Cancer Quality-of-Life Questionnaire-Core 30 (EORTC QLQ-C30). Multiple linear regression models were conducted for coping with potential confounding variables. We also examined PICC-related quality of daily life with a self-made questionnaire.  


Three hundred and fifty-seven cancer patients with PICC completed the survey in nine teaching hospitals. Lung cancer patients with PICC reported the worst dyspnea. Digestive tract cancer patients reported the worst appetite loss. Patients with hematologic malignancy reported the worst emotional, social function, fatigue and financial impact. Breast cancer patients reported better HRQOL. Baseline variables were proven not significant predictors of EORTC QLQ-C30 global health status. In self-made survey, pain after PICC insertion was null or a little in 98.6% of cancer patients. Limitation of upper extremity activity was null or a little in 94.1% of patients.  


HRQOL varies in different types of cancer patients with PICC. PICC may have a low impact on cancer patients’ HRQOL. Further large sample studies are needed.